Gstm1 breast cancer

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August undefined, 2024

WebSep 1, 2024 · Breast cancer is one of the most common cancers among women, and susceptibility is explained by genetic, lifestyle and environmental components. …

ORs for GSTM1 and GSTT1 breast cancer. Download Scientific …

WebApr 28, 2005 · Application of the new GSTM1 assay to a breast cancer case-control study revealed that the relative risk of breast cancer for the +/+ genotype compared to the -/- genotype was 2.83 (95% confidence interval 1.45-5.59; P=0.002), suggesting a protective effect of the GSTM1 deletion [Cancer Res. 64 (2004) 1233-1236]. WebNo correlation was found between GSTM1 null variant and breast cancer risk. Study showed that variant genotype of GSTM1 null polymorphism was associated with an increased risk of fetal growth restriction among mothers who were smokers. Among … politia mail

GSTP1 and cancer: Expression, methylation, polymorphisms and …

Web1 Introduction. Breast cancer is the most common malignant tumor and cause of cancer-related death among women, representing a major health problem worldwide. In … WebSeveral investigations of Hodgkin's lymphoma, ovarian cancer, colorectal cancer, and breast cancer have found improved survival rates associated with polymorphic forms of GSTT1, GSTM1, and GSTP1 ... Web// Jie Ma 1, * , Shao-Liang Zhu 2, * , Yang Liu 3, * , Xiang-Yang Huang 1 and Dan-Ke Su 1 1 Department of Radiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China 2 Department of Hepatobiliary Surgery, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China 3 Department of Radiotherapy, Affiliated Tumor Hospital of … politi visum

Effects of GSTT1 and GSTM1 polymorphisms in glutathione levels …

Association of glutathione S-transferase T1, M1, and P1 …

WebApr 3, 2024 · Taken together, our results suggest that GSTM1 polymorphism could be useful in the prediction of taxane-based neoadjuvant chemotherapy in ER-positive Chinese breast cancer patients, and that GSTM1 and GSTA1 expression are linked to docetaxel resistance. WebAug 1, 2024 · A multiplex qualitative real-time PCR method was used to detect the presence or absence of the GSTM1 and GSTT1 gene in the genomic DNA samples of the participants. Results: The frequencies of the GSTM1 and GSTT1 null genotypes in 198 breast cancer patients were 65.70% and 33.30%, respectively. The overall survival at 1, … politiaksjonWebAssociation between polymorphisms of glutathione S-transferase genes (GSTM1, GSTP1 and GSTT1) and breast cancer risk in a sample Iranian population Association between promoter methylation and expression of thyroid hormone receptor beta (THRβ) gene in patients with gastric cancer in an Iranian population. politi yrke

"WebMar 27, 2024 · Since oral cancer is a global health concern and alcohol and tobacco consumption are major risk factors involved in its carcinogenesis, the aim of this study was to evaluate the Fagerström and AUDIT tests as likely screening tools for oral cancer and their correlation with the expression of CYP1A1, GSTM1, GSTP1, and GSTT1 genes … " - Gstm1 breast cancer

Gstm1 breast cancer

The Fagerström and AUDIT Tests as Probable Screening Tools in …

WebDec 1, 2014 · The GSTM1-null genotype is also recognized as a risk factor for synchronous breast cancers and for breast cancer associated with one extramammary cancer (Chiril? et al., 2014). Recently, GSTM1 polymorphism has been suggested as a prognostic factor in women with breast cancer (Oliveira et al., 2014). WebNov 1, 2024 · PurposeDeletion of Glutathione S-Transferase Theta 1 (GSTT1) encoding gene is implicated in breast cancer susceptibility, clinical outcomes, and survival. Contradictory results have been reported in different studies. The present investigation based on a representative Pakistani population evaluated the GSTT1-absent genotype in …

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WebKalacas et al. [40] No association was found between GSTM1 and GSTT1 genetic polymorphisms and the risk of breast cancer development Almeida et al. [47] GSTM1 null genotype might be associated ... WebThe frequency of alleles in the GSTT1 and GSTM1 genes involved in phase II of xenobiotic transformation in long-lived people of subcarpathia Advances in Gerontology. — 2014. ... Evidence for association of the rs17822931-A Allele in ABCC11 with a decreased risk of estrogen receptor-negative breast cancer . Acta Medica Nagasakiensia. -2012; 56 ...

WebJan 10, 2024 · Introduction. Breast cancer (BC) is the most commonly diagnosed cancer in females and has the highest fatality rate among other cancer types (), competing with heart disease in being the leading cause of death worldwide ().BC is classified into five subtypes: luminal A, luminal B, luminal B-like, human epidermal growth factor receptor (HER)2, and … WebIn another meta-analysis study, the GSTM1 and GSTP1 polymorphisms (under allelic and dominant model) were found to be associated with increased breast cancer risk Asian population, especially in East Asians, and that the GSTT1 polymorphism might not be associated with breast cancer. 38 These differences between different meta-analyses …

WebEDRN; Data and Resources; Publications; Sensitivity to benzo(a)pyrene diol-epoxide associated with risk of breast cancer in young women and modulation by glutathione S-transferase polymorphisms: a case-control study. WebGSTM1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC.

WebJan 16, 2024 · Polymorphisms in the glutathione transferase enzymes (GSTs) genes have been associated with susceptibility to develop breast cancer (BC), but few are known regarding its role on this disease prognosis and impact on antioxidant status. This study evaluated the polymorphisms of GSTM1 and GSTT1 genes and their relationship with …

WebFeb 10, 2024 · Moreover, high expression of GSTP1 confers resistance of breast cancer cells to adriamycin by promoting autophagy . In addition, ... Vutuc C and Micksche M: Polymorphisms of glutathione-S-transferase genes (GSTP1, GSTM1 and GSTT1) and prostate-cancer risk. Int J Cancer. 95:152–155. 2001. View Article: Google Scholar: … political ka pita kaun haiWebTable 3. Association of GST gene polymorphism with breast cancer development. Discussion. The current study is the first to report association between breast cancer and GSTT1 and GSTM1 genes polymorphism in Ghanaian patients. The motivation for this study was to determine the association between GST polymorphic genes (GSTM1 and … politiaktionWebMar 10, 2024 · Fourteen previous meta-analyses have been published to analyze the polymorphisms of individual GSTM1 present/null, GSTT1 present/null, and GSTP1 … political party joanne motoikeWebUsing log-transformed whole blood arsenic concentrations as the dependent variable in a General Linear Model, there was a significant interaction between GSTP1 and autism spectrum disorder case status, but not for GSTT1 and GSTM1. In breast cancer cells, GSTP1 inhibits the expression of RIP140, a negative regulator of estrogen receptor alpha ... politica keynesianaWebJun 15, 2024 · GSTM1 may also affect OS in breast cancer . In gastric cancer, GSTM1 -wt patients show better tumor-related and disease-free survival [ 31 ]. However, in the study of Acevedo et al., there was no significant correlation between GSTM1 polymorphisms and prognosis of prostate cancer [ 32 ]. politica heloisa helenaWebSep 19, 2013 · The gene for glutathione-S-transferase (GST) M1 (GSTM1), a member of the GST-superfamily, is widely studied in cancer risk with … politia romana mailWebNational Center for Biotechnology Information politician jokes one-liners